Efficacy of Calcarea Fluoride in Atherosclerosis - Through A Case Study of Dyslipidemia 

Efficacy of Calcarea Fluoride in Atherosclerosis – Through A Case Study of Dyslipidemia 

ABSTRACT:

Atherosclerosis is the gradual build up of plaque in the walls of your arteries. This article contains following points- 1.why calcarea fluorica is remedy for atherosclerosis 2.case of dyslipidemia cured with calcarea fluoride 3.why calcarea fluoride is act on atherosclerosis with miasmatic correlation chronic miasm by Dr.J.H. ALLEN.

KEY WORDS: Atherosclerosis, hyperlipidemia, sycotic pathology, calcarea fluoride.

ABBREVIATIONS: LDL-low-density lipoprotein, ASCVD-Atherosclerotic cardiovascular disease, VLDL-very low density lipoprotein, sdLDL-Small dense low-density lipoprotein, TGs-triglyceride, HDL–High density lipoprotein, (PET)-CT-positron emission tomography-computed tomography.

WHAT IS ATHEROSCLEROSIS: 

Atherosclerosis is the gradual build up of plaque in the walls of your arteries. arteries are blood vessels that carry oxygen-rich blood to organs and tissues throughout your body. Plaque is a sticky substance made of fat, cholesterol, calcium and other substances.

WHAT IS DYSLIPIDEMIA:

Dyslipidemia is the imbalance of lipids such as cholesterol, low-density lipoprotein cholesterol, (LDL-C), triglycerides, and high-density lipoprotein (HDL). This condition can result from diet, tobacco exposure, or genetics and can lead to cardiovascular disease with severe complications. IT IS ALSO CALLED AS MIXED HYPERLIPIDEMIA. Mixed hyperlipidemia can be defined as fasting TGs >150 mg/dL and evidence of elevated cholesterol-containing lipoproteins (such as LDL-C >130 mg/dL or non-HDL-C >160 mg/dL). It is one of the most common types of lipid disorders seen in clinical practice, due both to genetic predisposition and influence of medical conditions and environmental factors (see below). It is generally associated with elevated risk of ASCVD, and therefore, patients with mixed hyperlipidemia should be carefully evaluated and managed to reduce this risk. Dyslipidemia is the most important risk factor for atherosclerosis. LDL, VLDL remnants, chylomicron remnants, small dense LDL(sdLDL), Lp(a), and oxidised LDL are pro-atherogenic and HDLs are anti-atherogenic lipoproteins. 

WHY CALCAREA FLUORICA IS REMEDY FOR ATHEROSCLEROSIS:

Calcarea fluorica is a powerful tissue remedy for hard ,stony glands ,varicose and enlarged veins and malnutrition of bones. It mainly acts on sycotic pathology. Because hyperlipidemia is accumulation of lipids into arteries, especially coronary arteries. As per 

THE CHRONIC MIASM BY DR. J.HENRY ALLEN , master said “that deposit themselves in the tissue in the typical tertiary sycosis or gouty diathesis ,although all are decidedly hurtful to the organism in the end”(part 1- psora and pseudo psora heart section). So dyslipidemia is sycotic pathology.

IMPORTANCE OF FLUORIDE ELEMENT IN DEVELOPMENT OF ATHEROSCLEROSIS:

The positron-emitting radiotracer 18F-sodium fluoride (18F-fluoride), commonly used to detect pathological metabolic activity in the skeletal system, can provide important insights into calcification activity within the cardiovascular system. 18F-fluoride binds to hydroxyapatite in proportion to the surface area of exposed crystal, such that it binds preferentially to areas of newly developing microcalcification where the surface area is many fold higher than large macroscopic deposits. Microcalcification is a key healing response in atherosclerotic plaque, closely associated with necrotic inflammation and high-risk disease, but ultimately leading to downstream coronary macro calcification and plaque stabilisation. 18F-fluoride positron emission tomography (PET)-CT, therefore, has the potential to act as a marker of disease activity in the coronary vasculature by targeting a biologically important stage of the disease. Indeed, ex vivo studies have confirmed the exquisite sensitivity of 18F-fluoride for early microcalcific deposits and its association with high-risk plaque features including macrophage infiltration and necrosis in atherosclerosis.

CASE OF DYSLIPIDEMIA:

PERSONAL HISTORY

PATIENT NAME – XYZ

AGE – 35/M

EDUCATION – PH.D SCHOLAR (ELECTRONICS AND COMMUNICATION)

CHIEF COMPLAINTS

A 35/m having a complaint of heaviness in chest sometimes after walking, ascending stairs with palpitation. Sometimes chest pain around the retrosternal area on and off, not more severe in intensity. All this complain occurs since 6 months but now it is increase since 7 days.

VITAL PARAMETERS

1.Blood Pressure – 140/84 Mm/Hg

2.Pulse – 100/Min

3.Respiratory Rate – 16/Min

4.Spo2 – 99%

5.No Pallor , No Anaemia , No Clubbing ,No Oedema,No Lymphadenopathy

6.No Xanthoma Or Lipid Deposition Around Knuckles 

7.Respiratory System – B/L Airway Entry Clear

8.Cardiovascular System – Hs1 Hs2 Heard Clear

9.Abdomen – Per Abdomen Soft And Non Tender

10.Central Nervous System – No Any Abnormal Neurological Sign.

11.Built – Obese ( Weight-90 Kg )

PAST HISTORY

1.Covid 19 – In 2021 (Home Quarantine)

FAMILY HISTORY

1.Father – Hypertension since 5 year took Allopathy Medicine, Businessman

2.Mother – No major Illness , Housewife

3.Grand Father – No major Illness

4.Grand Mother – Hypertension and Dyslipidemia 

PERSONAL HISTORY

He is a younger child in his house , took primary and higher secondary education from home town and is doing master degree in electronics and communication now he is living with his wife and one son in surat and doing ph.d since 3 years.all since childhood he is good at study but he doesn’t like mathematics. He is a diligent and hardworking child. He is polite , mild in nature. During consultation all answers were given before asking the wife. He was anxious and worried about this complain.he is a right handed person , will – weak , memory good , morals – good , speed – slow. He is timid and introverted .Before 8 months he had some issue with his father regarding money and his all savings till date were taken by his father and claiming that this money does not belong to him. He said all my savings are in a joint account of me and my father and he is not ready to give me money due to a dispute. This incident put him in a lot of anxiety and tension regarding money. He has constant thoughts regarding his money and he said he had stress regarding money. His father did not actually spend all the money but his father did not give his savings back to him. That’s why he has stress regarding money. Since that time all this complaining started.

PHYSICAL GENERAL

Appetite – 3 Meal/Day

Thirst – 3 Litres/Day

Stool – Occasionally Constipation

Urine – Pale Yellow

Sleep – Sound Sleep

Perspiration – On Back, Non Offensive, Non Staining

Dreams – Death Of Relatives

Desire – Sweets++ , Fatty Food 

Aversion – Sour And Bitter Food

 ANALYSIS OF CASE

JUSTIFICATION

REFERENCE: BOERICKE MATERIA MEDICA 

REMEDY – CALCAREA FLUOR 200 WEEKLY ONE DOSE 

1/12/2022 – FIRST DOSE GIVEN

15/12/2022 – Vital parameter normal , occasionally chest discomfort , no arm pain or specific cardiac symptoms. Due to sycotic pathology, weekly doses are repeated. Advice to come after 15 days with a lipid profile.

BEFORE TREATMENT – 1/12/2022

AFTER TREATMENT – 4/1/2023

4/1/2023 – NO CHEST PAIN OR ANY SPECIFIC SYMPTOMS , SL GIVEN FOR 1 MONTH

7/2/2023 – BETTER , SL FOR 1 MONTH

1/3/2023 – BETTER , SL FOR 1 MONTH

3/4/2023 – BETTER , SL FOR 1 MONTH

5/5/2023 – BETTER , SL FOR 1 MONTH

1/6/2023 – BETTER , SL FOR 1 MONTH

20/7/2023 – AGAIN LIPID PROFILE DONE.

Patient is asymptomatic and stop his treatment

CONCLUSION: 

As Homoeopathy treats patients as a whole, not the clinical diagnosis. By anti-miasmatic approach after finding core of patient we can select anti miasmatic remedy which can brings cure to the patient also role of homoeopathic repertory is extremely essential to reach out most suitable remedy for patient.

REFERENCES:

1.HARRISON’S PRINCIPLES OF INTERNAL MEDICINE 21 EDITION.

2.BOERICKE’S MATERIA MEDICA

3.https://www.ncbi.nlm.nih.gov/books/NBK560891/#:~:text=Dyslipidemia%20is%20the%20imbalance%20of,cardiovascular%20disease%20with%20severe%20complications.

4. https://my.clevelandclinic.org/health/diseases/16753-atherosclerosis-arterial-disease

5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771641/

6.https://pubmed.ncbi.nlm.nih.gov/21226274/#:~:text=Dyslipidemia%20is%20the%20most%20important,HDLs%20are%20anti%2Datherogenic%20lipoproteins.

7.THE CHRONIC MIASMS WITH REPERTORY – J.HENRY ALLEN M.D

About the author

Dr. Akash Chudasama

Dr Akash Chudasama - Md Scholar Part 1 in Practice Medicine