Hypercholesterolemia Effectively Managed with Homeopathic Medicine Gautteria Gaumeri (Yumel): Results from a Clinical Study in Academic Clinical Set Up in North India

ABSTRACT
Background: Hypercholesterolaemia increases the risk of atherosclerosis, subsequently IHD. Herbal-homeopathic medicines are unexplored as lipid-lowering agents. This study presents safety and efficacy outcomes of homeopathic Gautteria gaumeri Q, in treatment of hypercholesterolaemia.
Methods: This was a homoeopathic registry in real world population. A group of 29 subjects with mild to moderate hypercholesterolaemia with or without statin therapy were included in the study at a single centre in Udaipur, India. All subjects were given 10-15 drops of Gautteria gaumeri Q thrice in a day for 2 months and were followed fortnightly.
Results: The sample demographics were similar to typical Indian demographics (age 43±14 years, height 166.5cm, BMI 21kg/m²) having age 49±6 years, gender ratio 0.81 with 13 (45%) males and 16 (55%) females, height 157.07±26.18 cms and weight 71.5±11.78 Kg. The comorbidity included diabetes (44.83%), hypertension (68.97%), current smoking (44.83%) and CAD (31.03%). Thirteen (44.83%) subjects were taking statins for minimum 6 months. At baseline, mean TC, HDL, LDL, VLDL cholesterols and triglycerides were 223±25.8, 41.45±4.82, 150.9±25.97, 30.66±6.38 and 223±34.81 respectively. TC: HDL and LDL: HDL ratios were 5.44±0.82 and 3.69±0.77 respectively. At 2 months, TC reduced by 22.21 (9.96%), triglycerides, LDL and VLDL cholesterol demonstrated 39.55 (17.70%), 24.66 (16.34%) and 3.35 (10.91%) reduction respectively. HDL increased by 5.84 (14.09%). Proportion of population at risk defined as TC >200, LDL >120, VLDL >30, HDL <30 and triglycerides >200 was reduced by 17.24%, 31.04%, 13.79%, 100% and 31.03% respectively. (Baseline n=13). There were no ADRs in the study. Gauttaria gaumeri was proved to be efficacious in treatment of hypercholesterolaemia.
Conclusions: Guatteria gumeri was observed to be efficacious in controlling hypercholesterolaemia. There was no significant effect of statin therapy prior to starting Guatteria gaumeri Q. No safety issues were reported in the study.
ACKNOWLEDGEMENTS
Authors would like to acknowledge and thank B Jain Pharmaceuticals for supplying proprietary investigational medicine free of cost for the study and for providing unconditional education grants for conduct of blood tests.
Reproduced from online publication of : International Journal of Advances in medicine, for full article visit : , http://www.ijmedicine.com/index.php/ijam/article/view/551/591,