MIT or Molecular Imprints Therapeutics refers to a scientific hypothesis that proposes a
rational model for biological mechanism of homeopathic therapeutics.
According to MIT hypothesis, potentization involves a process of ‘molecular imprinting’,
where in the conformational details of individual drug molecules are ‘imprinted’ or engraved
as hydrogen-bonded three dimensional nano-cavities into a supra-molecular matrix of water
and ethyl alcohol, through a process of molecular level ‘host-guest’ interactions. These
‘molecular imprints’ or ‘hydrosomes’ are the active principles of post-avogadro dilutions
used as homeopathic drugs.
Due to ‘conformational affinity’, molecular imprints can act as ‘artificial key holes’ or
‘ligand binds’ for the specific drug molecules used for imprinting, and for all pathogenic
molecules having functional groups ‘similar’ to those drug molecules. When used as
therapeutic agents, molecular imprints selectively bind to the pathogenic molecules having
conformational affinity and deactivate them, thereby relieving the biological molecules from
the inhibitions or blocks caused by pathogenic molecules. According to MIT hypothesis, this
is the biological mechanism of high dilution therapeutics involved in homeopathic cure.
According to MIT hypothesis, ‘Similia Similibus Curentur’ means, diseases expressed
through a particular group of symptoms could be cured by ‘molecular imprints’ forms of drug
substances, which in ‘molecular’ or crude forms could produce ‘similar’ groups of symptoms
in healthy individuals. ‘Similarity’ of drug symptoms and diseaes indicates ‘similarity’ of
pathological molecular inhibitions caused by drug molecules and pathogenic molecules,
which in turn indicates conformational ‘similarity’ of functional groups of drug molecules
and pathogenic molecules. Since molecular imprints of ‘similar’ molecules can bind to
‘similar’ ligand molecules by conformational affinity, they can act as therapeutic agents when
applied as indicated by ‘similarity of symptoms’.
No body in the whole history could so far propose a hypothesis about homeopathy as
scientific, rational and perfect as MIT, explaining the molecular process involed in
potentization, and the biological mechanism involved in ‘similia similibus curentur’, in a way
fitting well to modern scientific knowledge system.